CRYSTALLISATION PROCESS FOR 1-(ß-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-FLUOROPHENYL)-2-THIENYLMETHYL] BENZENE
摘要
<p>The present invention relates to a crystallisation procedure to obtain 1 -(ß-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties.</p>
申请公布号
WO2011003976(A1)
申请公布日期
2011.01.13
申请号
WO2010EP59817
申请日期
2010.07.08
申请人
JANSSEN PHARMACEUTICA NV;RAMMELOO, THOMAS JOACHIM LANDEWALD;DE KEYSER, RUBEN;SCHILDERMANS, GUSTAAF JOZEF PETRUS
发明人
RAMMELOO, THOMAS JOACHIM LANDEWALD;DE KEYSER, RUBEN;SCHILDERMANS, GUSTAAF JOZEF PETRUS
