发明名称 PROCESS FOR THE PREPARATION OF GRIGNARD COMPOUNDS
摘要 The invention relates to a process for the preparation of Grignard compounds using a continuous method which involves the reaction of an organic halide dissolved in an organic solvent with metallic magnesium which, together with the activator solution in an organic solvent, fills the flow reactor or optionally a system of flow reactors, and subsequently, the resulting reaction mixture is fed into the terminal flow reactor containing metallic magnesium in order to achieve complete conversion of the organic halide, whereby preferably the organic solvent is re-circulated to flow reactors in a form of vapour.
申请公布号 WO2010117285(A2) 申请公布日期 2010.10.14
申请号 WO2010PL00024 申请日期 2010.03.29
申请人 ZAKLADY FARMACEUTYCZNE POLPHARMA SA;SZEJA, WIESLAW;HELMAN, JAN;KIRAGA, KRZYSZTOF;DERFLA, SEBASTIAN 发明人 SZEJA, WIESLAW;HELMAN, JAN;KIRAGA, KRZYSZTOF;DERFLA, SEBASTIAN
分类号 C07F3/02 主分类号 C07F3/02
代理机构 代理人
主权项
地址