发明名称 |
CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND USES THEREOF |
摘要 |
The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid. Also provided by this invention is multiparticulate, controlled release oral solid formulations of levodopa comprising: i) a controlled release component comprising a mixture of levodopa, a decarboxylase inhibitor and a rate controlling excipient; ii) a carboxylic acid component; and iii) an immediate release component comprising a mixture of levodopa and a decarboxylase inhibitor. |
申请公布号 |
EP2234963(A1) |
申请公布日期 |
2010.10.06 |
申请号 |
EP20080866933 |
申请日期 |
2008.12.26 |
申请人 |
IMPAX LABORATORIES, INC. |
发明人 |
HSU, ANN;KOU, JIM, H.;ALANI, LAMAN, LYNN |
分类号 |
A61K9/22;A61K31/198;A61K45/06;C07C229/00 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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