| 摘要 |
The invention relates to compounds of the formula I, or pharmaceutically acceptable salts thereof: wherein: Z = O or S; n = 1 - 3; R3 = -CO2R8, -C(O)SR8, -C(O)NHR8, -C(S)OR8, -C(S)SR8, -C(S)NHR8, -C(NH)SR8 or -C(NH)NHR8, wherein R8 is -H or alkyl; R4 =.H, -CH2R5 or -CH2CH2R5, wherein R5 independently has one of the meanings of R3; B= -NR2-, -CH2NR2-, -CH2CH2NR2-, -CH2CHR7 - or -CH2O-, wherein R2 is H or a C1 3 alkyl, alkenyl or alkynyl group, and R7 is H or a C13 alkyl or alkoxy group; A = wherein R1 =-NH2 or -OH, and C and D are each, independently, a 5-or 6- membered, substituted or unsubstituted, aromatic or non-aromatic ring which may also contain one or more heteroatoms, and C is connected to group B in any available position.
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