发明名称 |
FERMENTATION OF PRAVASTATIN |
摘要 |
The present invention provides a microorganism containing a compactin biosynthesis gene and a gene for conversion of compactin into pravastatin. In a preferred example, said compactin biosynthesis gene is mIcA and/or mIcB and/or mIcC and/or mIcD and/or mIcE and/or mIcF and/or mIcG and/or mIcH and/or mIcR and said gene for conversion of compactin into pravastatin is a hydroxylase gene. Furthermore, the present invention provides a method for producing a compound of interest such as a statin. In a preferred example said statin is pravastatin.
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申请公布号 |
US2010048938(A1) |
申请公布日期 |
2010.02.25 |
申请号 |
US20070305591 |
申请日期 |
2007.06.19 |
申请人 |
BERG MARCO ALEXANDER VAN DEN;MEIJRINK BERNARD |
发明人 |
BERG MARCO ALEXANDER VAN DEN;MEIJRINK BERNARD |
分类号 |
C07C69/76;C12N1/15;C12P1/02;C12P7/62 |
主分类号 |
C07C69/76 |
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