发明名称 |
Gene encoding a nonribosomal peptide synthetase for the production of ramoplanin |
摘要 |
The present invention relates to isolated genetic sequences encoding nonribosomal peptide synthetase (NRPS) proteins which direct the biosynthesis of the antibiotic ramoplanin in microorganisms such as Actinoplanes sp. The isolated gene sequences serve as substrates for bioengineering of antibiotic structures.
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申请公布号 |
US7635765(B2) |
申请公布日期 |
2009.12.22 |
申请号 |
US20050205109 |
申请日期 |
2005.08.17 |
申请人 |
THALLION PHARMACEUTICALS, INC. |
发明人 |
FARNET CHRIS M.;ZAZOPOULOS EMMANUEL;STAFFA ALFREDO |
分类号 |
C07H21/04;C12N15/09;C07K9/00;C07K14/00;C07K14/365;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/52;C12N15/31;C12N15/52;C12P21/06 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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