| 摘要 |
<p>Aminoindolizine compounds (I) and their acid addition salts and solvates are new. Aminoindolizine compounds of formula (I) and their acid addition salts and solvates are new. R 11-10C alkyl (optionally substituted by OH or OR 19), H, sulfur radical comprising SR, SO 2CH 3, nitrogen radical comprising NH 2, NHR 7or NR 7R 8, OR 9, COOH, CONH 2, CONHR 11or CONR 11R 12; R 191-6C alkyl optionally substituted by OH; R : 1-6C alkyl or aryl; either R 7, R 81-6C alkyl (optionally substituted by OH, NH 2, 1-6C mono- or dialkylamino, carboxamido, ureido or guanidinyl, optionally interrupted by O or N(R 13)); or NR 7R 85-7 membered heterocycle; R 13H or 1-6C alkyl; R 91-6C alkyl (optionally substituted by OH or 1-6C alkoxy); either R 11, R 121-6C alkyl optionally interrupted by N(R 14); or NR 11R 125-7 membered heterocycle; R 14H or 1-6C alkyl optionally substituted by OH; R 21-6C alkyl, H, COOH, CN, [Image] [Image].</p> |
