发明名称 QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS
摘要 The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
申请公布号 US2009118261(A1) 申请公布日期 2009.05.07
申请号 US20050574031 申请日期 2005.08.26
申请人 ASTRAZENECA AB 发明人 AQUILA BRIAN;DAKIN LESLIE;EZHUTHACHAN JAYACHANDRAN;LEE STEPHEN;LYNE PAUL;PONTZ TIMOTHY;ZHENG XIAOLAN
分类号 A61K31/55;A61K31/496;A61K31/517;A61K31/519;A61K31/5377;A61P35/00;C07D239/72;C07D403/02;C07D413/02;C07D471/02 主分类号 A61K31/55
代理机构 代理人
主权项
地址