STABILIZED THERAPEUTIC COMPOSITIONS AND FORMULATIONS

摘要

The invention relates to pharmaceutically acceptable formulations comprising an active pharmaceutical ingredient such as androst-5-ene-3ß, 17ß-diol, androst-5-ene- 3ß,7ß, 17ß-triol or derivatives of either of these compounds and an air oxidizable excipient that have been stabilized with respect to efficacy. Use of the efficacy-stabilized formulations to treat a number of conditions or symptoms thereof, such as a symptom associated with exposure to radiation is described.