发明名称 PHARMACEUTICAL CONTAINING PPAR.ALPHA. AGONIST
摘要 It is intended to provide an agent for promoting the growth of meibomian gland epithelial cells and corneal epithelial cells, and a therapeutic agent for eye diseases such as meibomian gland dysfunction and dry eyes. A prepar ation containing as an active ingredient, [3-[2-[4-isopropyl-2-(4-trifluorom ethyl)phenyl-5-thiazolyl]ethyl]-5-methyl-1,2-benzisoxazol-6-yl]oxyacetate, [ 4-[3-[2-(4-trifluoromethyl)phenyl-4-isopropyl-5-thiazolyl] propionyl]2-methy lphenoxy]acetate or [4-[3-[2-(2-hydroxy-4-chlorophenyl)-5-isopropyl-4-oxazol yl]propionyl]-2-methylphenoxy]acetate or a pharmacologically acceptable salt thereof is used as the agent for promoting the growth of meibomian gland ep ithelial cells or corneal epithelial cells and the therapeutic agent for eye diseases such as meibomian gland dysfunction and dry eyes.
申请公布号 CA2687957(A1) 申请公布日期 2008.11.27
申请号 CA20082687957 申请日期 2008.05.20
申请人 NIPPON CHEMIPHAR CO., LTD.;SENJU PHARMACEUTICAL CO., LTD. 发明人 INOUE, JUN;HANANO, IKUKO;NAKAMURA, YOSHIKUNI
分类号 C07D263/32;A61K31/421;A61K31/426;A61K31/427;A61P27/02;A61P27/04;A61P27/14;A61P37/08;A61P43/00;C07D277/24;C07D417/06 主分类号 C07D263/32
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