摘要 |
PROBLEM TO BE SOLVED: To synthesize a new compound having a 1,4-benzoxazin-3-one skeleton, and to find out pharmacological actions of the compound. SOLUTION: This invention relates to a compound represented by formula [I] (wherein ring A represents a ring of benzene, thiophene, thiazole, furan or the like; R<SB>1</SB>and R<SB>2</SB>are each independently an hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aromatic heterocyclic group or the like; X represents a single bond, C=C, CH<SB>2</SB>-O, O-CH<SB>2</SB>, NH-CH<SB>2</SB>, CH<SB>2</SB>-NH or the like; Y represents a hydroxy group, an alkyl group, an alkoxy group, NR<SB>3</SB>R<SB>4</SB>or the like; and R<SB>3</SB>and R<SB>4</SB>are each independently a hydrogen atom, a hydroxy group, an alkyl group, an alkoxy group, a cycloalkyl group, an aryl group, an aromatic heterocyclic group, a non-aromatic heterocyclic group or the like) or a salt thereof. COPYRIGHT: (C)2009,JPO&INPIT
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