发明名称 |
COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF FIBROTIC, INFLAMMATORY, AND NEOVASCULARIZATION CONDITIONS OF THE EYE |
摘要 |
The present invention relates to compositions and methods for prevention and treatment of ocular diseases and conditions characterized by aberrant fibrogenesis or scarring, inflammation and/or aberrant neovascularization or angiogenesis. The compositions and methods of the invention utilize immune-derived moieties that are specifically reactive against bioactive lipids and which are capable of decreasing the effective concentration of said bioactive lipid. In some embodiments, the immune-derived moiety is a monoclonal antibody that is reactive against sphingosine-1-phosphate (S1P) or lysophosphatidic acid (LPA).
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申请公布号 |
US2008213274(A1) |
申请公布日期 |
2008.09.04 |
申请号 |
US20070841363 |
申请日期 |
2007.08.20 |
申请人 |
SABBADINI ROGER A;GARLAND WILLIAM A;STOLLER GLENN L |
发明人 |
SABBADINI ROGER A.;GARLAND WILLIAM A.;STOLLER GLENN L. |
分类号 |
A61K39/395;A61P27/02 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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地址 |
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