ХИРАЛЬНЫЕ ПРОИЗВОДНЫЕ ГЕПТИНА ДЛЯ ПОЛУЧЕНИЯ ЭПОТИЛОНОВ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ

摘要

The invention relates to a new synthetic process for the production of key intermediates useful in the synthesis of epothilones or epothilone derivatives, to certain compounds used to produce these key intermediates and to a process to produce said compounds. The intermediates used are represented by formulae II and III, wherein R is selected from H, alkyl and substituded alkyl and X1 is an oxygen protecting group.