发明名称 |
HIGH DOSE ORALLY DISSOLVABLE/DISINTEGRABLE LYOPHILIZED DOSAGE FORM |
摘要 |
The present invention provides an orally dissolvable/disintegrable, lyophilized dosage form including a protected granulate comprising an active ingredient and a protective granulation binder, which substantially protects the form and/or attributes of a granulate and/or active ingredient, and participates in masking bad tasting active ingredients, such as sulfur-containing materials, and a matrix, and a method for making same. There is also provided a method of treating a patient using any orally dissolvable/disintegrable lyophilized dosage form comprising the steps of placing the dosage form in the mouth of a patient in need of treatment, allowing the dosage form to disintegrate/dissolve sufficiently to allow it, and in particular, the protected granulate, to be swallowed as a solution, suspension or slurry, and swallowing the at least partially disintegrated/dissolved dosage form. |
申请公布号 |
WO2008013808(A3) |
申请公布日期 |
2008.05.15 |
申请号 |
WO2007US16638 |
申请日期 |
2007.07.24 |
申请人 |
CIMA LABS INC.;CEPHALON FRANCE;HAMED, EHAB;KHANKARI, RAJENDRA, K.;MOE, DEREK;NGUYEN, TAM |
发明人 |
HAMED, EHAB;KHANKARI, RAJENDRA, K.;MOE, DEREK;NGUYEN, TAM |
分类号 |
A61K9/00;A61K9/16 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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