| 发明名称 |
Recombinant P. falciparum merozoite protein-1 42 vaccine |
| 摘要 |
In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1<SUB>42</SUB>. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1<SUB>42 </SUB>is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
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| 申请公布号 |
US2008075741(A1) |
申请公布日期 |
2008.03.27 |
| 申请号 |
US20070889578 |
申请日期 |
2007.08.14 |
| 申请人 |
UNITED STATES ARMY MEDICAL RESEARCH AND COMMAND |
发明人 |
ANGOV EVELINA;LYON JEFFREY A.;DARKO CHRISTIAN A.;COHEN JOE D. |
| 分类号 |
A61K39/02;A61K39/00;A61P31/04;C07K14/445;C07K16/12;C12N1/21;C12N15/00;C12N15/30;C12N15/67;C12P21/00;C12P21/02;C12P21/04;G01N33/554 |
主分类号 |
A61K39/02 |
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