| 摘要 |
<p>A method for controlling a freeze drying process in a freeze dryer apparatus (100) provided with a drying chamber (101) having temperature-controlled shelf means (104) supporting containers (50) containing a product (30) to be freeze dried, comprises during a primary drying phase of said freeze drying process the steps of:
- isolating said drying chamber (101) and sensing and collecting pressure values (p c,mes ) inside said drying chamber (101) for a defined pressure collecting time (t f ) and a shelf temperature (T shelf ) of said temperature-controlled shelf means (104) (Step 1);
- calculating a product temperature (T) and a plurality of process/product related parameters (T i0 , R p , K v , L frozen, T B ) (Step 2);
- calculating a new shelf temperature (T' shelf ) according to said product temperature (T) so as to maximize a heat provided by said temperature-controlled shelf means (104) and so as to drive the product (30) to a desired target temperature (Step 3).</p> |
