发明名称 |
Human antihuman MCP-1 antibody and antibody fragment thereof |
摘要 |
A substance effective for treating immunopathy where MCP-1 is involved is provided. scFv having a high affinity to human MCP-1 was obtained using phage antibody technique. Based on information of VH chain and VL chain obtained from said scFv, a human anti-human MCP-1 antibody and a human anti-human MCP-1 antibody fragment are obtained. Said antibody and antibody fragment are expected to be useful as a medicament for treating inflammation and immunopathy caused by MCP-1.
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申请公布号 |
US7342106(B2) |
申请公布日期 |
2008.03.11 |
申请号 |
US20050527823 |
申请日期 |
2005.03.14 |
申请人 |
JUDICIAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
SUGIMURA KAZUHISA;NAKASHIMA TOSHIHIRO;NISHIHARA TSUKASA |
分类号 |
C07H21/02;A61P9/10;A61P29/00;A61P37/06;A61P43/00;C07K16/00;C07K16/24;C12N15/13 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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