发明名称 METHOD FOR PRODUCING NITROGEN-CONTAINING FUSED RING COMPOUND
摘要 <p>It is intended to provide a method for producing an excellent compound effective in the treatment, prevention or the like of pathological conditions associated with uric acid such as hyperuricemia, tophus, acute gouty arthritis, chronic gouty arthritis, gouty nephropathy, urolithiasis, renal dysfunction, coronary artery disease and ischemic heart disease and a method for purifying the same. By reacting a compound represented by the general formula [3] or a salt thereof and a compound represented by the general formula [4] or a reactive derivative thereof, a compound represented by the general formula [2] or a pharmaceutically acceptable salt thereof can be produced. Further, the crystallization of the compound represented by the general formula [2] can be conduced with an industrially excellent workability and a high quality crystal of the compound represented by the general formula [2] can be obtained. [3] [4] [2] (In the formulae, each symbol is as described in the specification.)</p>
申请公布号 WO2007139002(A1) 申请公布日期 2007.12.06
申请号 WO2007JP60678 申请日期 2007.05.25
申请人 JAPAN TOBACCO INC.;HIRATA, KAZUYUKI;OGAWA, NAOKI;SHINAGAWA, YUKO;KIGUCHI, TOSHIHIRO;INOUE, TERUHIKO;KOMEDA, YASUKI;YAMASHITA, ICHIRO;KAMIYA, YUKIHIRO 发明人 HIRATA, KAZUYUKI;OGAWA, NAOKI;SHINAGAWA, YUKO;KIGUCHI, TOSHIHIRO;INOUE, TERUHIKO;KOMEDA, YASUKI;YAMASHITA, ICHIRO;KAMIYA, YUKIHIRO
分类号 A61K31/498;C07D209/12;A61K31/404;A61K31/47;A61K31/538;A61K31/5383;A61K31/5415;A61K31/55;A61K31/5513;A61K31/553;A61P3/06;A61P3/10;A61P9/12;A61P13/02;C07D215/08;C07D223/16;C07D265/36;C07D241/42;C07D243/14;C07D265/34;C07D265/38;C07D267/14;C07D279/16;C07D498/04 主分类号 A61K31/498
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