PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL AND FOOD ADDITIVE COMPOUNDS
摘要
This invention provides an improved synthesis of polymer conjugates of formula (I), of agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using "Mitsunobu" or related reaction conditions.
申请公布号
WO2007137260(A2)
申请公布日期
2007.11.29
申请号
WO2007US69464
申请日期
2007.05.22
申请人
ELAN PHARMACEUTICALS, INC.;KONRADI, ANDREI, W.;SMITH, JENIFER, L.