<p>A highly safe immune adjuvant exhibiting a potent immunostimulating effect, which comprises two or more different microparticulate immunostimulator carriers and one or more immunostimulators carried on the carriers, respectively, each of the microparticulate immunostimulator carriers comprising the combination of (a) an inorganic substance having such a size that it can be phagocytized by a cell (e.g., microparticulate calcium phosphate) and (b) a precipitate produced by coacervation of a soluble protein and a mucopolysaccharide.</p>