发明名称 AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS
摘要 Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject. The compounds include azaindoles of the formula below [insert figure 6c] in which at least one of CR4, CR5, CR6 and CR7 is replaced by N, and the groups R1-R7 are defined as in claim 1.
申请公布号 WO2007056184(A3) 申请公布日期 2007.07.05
申请号 WO2006US43036 申请日期 2006.11.03
申请人 ILYPSA, INC.;CHANG, HAN-TING;CHARMOT, DOMINIQUE;GLINKA, TOMASZ;COPE, MICHAEL JAMES;GOKA, ELIZABETH;SHAO, JUN;MONG, TONY KWOK-KONG;CHEN, SHIAH-YUN;BUYSSE, JERRY M. 发明人 CHANG, HAN-TING;CHARMOT, DOMINIQUE;GLINKA, TOMASZ;COPE, MICHAEL JAMES;GOKA, ELIZABETH;SHAO, JUN;MONG, TONY KWOK-KONG;CHEN, SHIAH-YUN;BUYSSE, JERRY M.
分类号 C07D471/04;A61K31/437;A61K31/5025;A61P3/06;C07D487/04 主分类号 C07D471/04
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