摘要 |
Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject. The compounds include azaindoles of the formula below [insert figure 6c] in which at least one of CR4, CR5, CR6 and CR7 is replaced by N, and the groups R1-R7 are defined as in claim 1. |
申请人 |
ILYPSA, INC.;CHANG, HAN-TING;CHARMOT, DOMINIQUE;GLINKA, TOMASZ;COPE, MICHAEL JAMES;GOKA, ELIZABETH;SHAO, JUN;MONG, TONY KWOK-KONG;CHEN, SHIAH-YUN;BUYSSE, JERRY M. |
发明人 |
CHANG, HAN-TING;CHARMOT, DOMINIQUE;GLINKA, TOMASZ;COPE, MICHAEL JAMES;GOKA, ELIZABETH;SHAO, JUN;MONG, TONY KWOK-KONG;CHEN, SHIAH-YUN;BUYSSE, JERRY M. |