发明名称 6-MONOACETYLMORPHINE DERIVATIVE USEFUL FOR IMMUNOASSAY
摘要 PROBLEM TO BE SOLVED: To provide a chemical analogue useful in producing a conjugate useful in the development of an antibody recognizing 6-MAM(6-monoacetylmorphine) and 6-MAC(6-monoacetylcodeine) and also useful in an immunoassay for detecting 6-MAM and 6-MAC. SOLUTION: The chemical analogue is a compound of the structure shown in the figure, wherein R is a saturated or unsaturated and substituted or nonsubstituted straight chain or branched chain containing a 0-10 carbon atom(s) or heteroatom(s), L is a linker group containing 0-2 substituted or nonsubstituted aromatic ring(s), X is NH or O, and Y is an activated ester group. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007161712(A) 申请公布日期 2007.06.28
申请号 JP20060334322 申请日期 2006.12.12
申请人 F HOFFMANN LA ROCHE AG 发明人 GHOSHAL MITALI;ROOT RICHARD TERRY;SIGLER GERALD F
分类号 C07D489/00;A61K39/385;C07D489/02 主分类号 C07D489/00
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