摘要 |
<p>Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody,expression and/or reduce or eliminate mis-spliced and/or intron read-through(IRT) by-products are disclosed. The invention also provides methods for producingproteins devoid of mis-spliced and/or intron read-through by-products by theuse of such vectors in host cells under cell culture conditions suitable for recombinantprotein expression.</p> |