摘要 |
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing or treating degenerative disorders of muscle, bone, or insulin metabolism. |
申请人 |
WYETH |
发明人 |
AGHAJANIAN, JANE;VELDMAN, GEERTRUIDA M.;WHITTEMORE, LISA-ANNE;BRIDGES, KRISTIE, GROVE;BOUXSEIN, MARY;WOLFMAN, NEIL, M.;DAVIES, MONIQUE, V.;O'HARA, DENISE;KHURANA, TEJVIR, S. |