发明名称 Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators
摘要 The invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, A, B, D, m, n, x, and y are defined as described in the specification. The invention additionally provides a pharmaceutically composition comprising the compound of formula I, together with a method of using the same to treat or prevent neurological and psychiatric disorders. The compounds are useful in therapy related to the treatment or prevention of mGluR2 receptor-mediated disorders.
申请公布号 US2007032469(A1) 申请公布日期 2007.02.08
申请号 US20060490090 申请日期 2006.07.21
申请人 NPS PHARMACEUTICALS 发明人 ISAAC METHVIN;SLASSI ABDELMALIK;EGLE IAN;MA FUPENG
分类号 A61K31/55;A61K31/519;A61K31/5383;A61K31/542;C07D487/14;C07D491/14;C07D498/14 主分类号 A61K31/55
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