发明名称 METHODE ZUR BEHANDLUNG VON KRANKHEITEN DURCH VERÄNDERUNG DER WECHSELWIRKUNG ZWISCHEN NATURAL KILLER REZEPTOREN AUF T-ZELLEN MIT IHREN JEWEILIGEN LIGANDEN
摘要 <p>Methods of treating psoriasis and other cutaneous and extracutaneous disorders mediated by immunocytes bearing natural killer-type receptors (NK-T cells) for classical or non-classical MHC-class I-like molecules (and their functional homologs). The methods of the present invention include antagonizing the activation mediated by NK-type receptors for those diseases in which such immunocytes are causing or exarcebating the disease, as well as for methods to augment the immune response in infectious (viral, bacterial, or fungal) or neoplastic conditions in which such activation would be beneficial.</p>
申请公布号 DE69933218(D1) 申请公布日期 2006.10.26
申请号 DE1999633218 申请日期 1999.06.28
申请人 NICKOLOFF, BRIAN J. 发明人 NICKOLOFF, BRIAN J.
分类号 C07K16/28;G01N33/50;A61K39/395;A61K45/00;A61P17/00;A61P17/06;A61P17/14;A61P35/00;A61P37/04;A61P43/00;C12Q1/02;C12Q1/68;G01N33/48 主分类号 C07K16/28
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