发明名称 |
Materials and methods for treating hypercholesterolemia |
摘要 |
The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can be advantageously used to treat patients suffering hypercholesterolemia.
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申请公布号 |
US2006116418(A1) |
申请公布日期 |
2006.06.01 |
申请号 |
US20050220364 |
申请日期 |
2005.09.06 |
申请人 |
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发明人 |
DRUZGALA PASCAL;ZHANG XIAOMING;PFISTER JURG R. |
分类号 |
A61K31/405;A61K31/22;A61K31/343;A61K31/353;A61K31/40;A61K31/404;A61K31/4418;A61K31/47;A61K31/505;A61K31/56;A61K31/573;A61K31/575;A61P3/06;A61P43/00;C07C69/675;C07C69/708;C07C69/732;C07D207/34;C07D209/12;C07D209/18;C07D209/24;C07D209/42;C07D213/30;C07D213/55;C07D213/80;C07D215/12;C07D215/14;C07D239/42;C07D307/79;C07D307/80;C07D311/72;C07J3/00;C07J5/00;C07J9/00 |
主分类号 |
A61K31/405 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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