<p>This invention provides cellular regulators of antitumor agent apratoxin A. The invention also provides methods for identifying novel antitumor compounds using these cellular regulators of apratoxin A. The methods comprise first screening test agents for modulators of a cellular regulator of apratoxin A and then further screening the identified modulating agents for antitumor activities. The invention further provides methods and pharmaceutical compositions for treating tumors in a subject.</p>
申请公布号
WO2006015190(A2)
申请公布日期
2006.02.09
申请号
WO2005US26927
申请日期
2005.07.28
申请人
IRM LLC;THE SCRIPPS RESEARCH INSTITUTE;LUESCH, HENDRIK;CHANDA, SUMIT