DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR NPY4 (NPY4)

摘要

The invention provides a human NPY4 which is associated with the gastrointestinal and liver diseases, cardiovascular disorders, metabolic diseases, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders, reproduction disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of gastrointestinal and liver diseases, cardiovascular disorders, metabolic diseases, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders, reproduction disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of NPY4 as well as pharmaceutical compositions comprising such compounds.