Aliphatic nitrogen-containing 5-membered ring compound

摘要

Disclosed are aliphatic nitrogen-containing 5-memebered ring compounds of formula (I), wherein: A is -CH2- or -S-, R1 is H, lower alkyl, hydroxy lower alkyl, or lower alkoxy lower alkyl, X is -N(R3)-, -O- or -CO-, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases mediated by inhibiting dipeptidylpeptidase IV activity.