| 摘要 |
Compounds of formula (I) wherein X is a fluorine or a chlorine atom; the methyl groups located at the 2- and 5-position of the piperazine ring are in trans~configuration to each other; Y is NH or O; Rl is selected from hydroge n, chloro, bromo, nitro, methyl or trifluoromethyl; R2 is selected from hydroge n, halo, methyl, trifluoromethyl, methoxy or trifluoromethoxy; or a pharmaceutically acceptable salt or solvate thereof, pharmaceutical compositions containing them and their use in therapy for treating inflammatory, autoimmune, proliferative or hyperproliferative diseases.</SDO AB>
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