| 发明名称 |
Methods and compositions for treating Alzheimer's disease |
| 摘要 |
The present invention provides methods for reducing the efflux of cholesterol and/or secreted Abeta in the brain, as well as methods for treating Alzheimer's disease, by inhibit the expression and/or activity of LXR and/or ABCA1. Compositions comprising agents for performing the methods also are provided.
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| 申请公布号 |
US2005095239(A1) |
申请公布日期 |
2005.05.05 |
| 申请号 |
US20030664414 |
申请日期 |
2003.09.17 |
| 申请人 |
REBECK G. W.;DENG AMY;FUKUMOTO HIROAKI;IRIZARRY MICHAEL;FITZGERALD MICHAEL |
发明人 |
REBECK G. W.;DENG AMY;FUKUMOTO HIROAKI;IRIZARRY MICHAEL;FITZGERALD MICHAEL |
| 分类号 |
A61K31/195;A61K31/66;A61K31/7088;A61K39/395;A61K45/06;A61K48/00;A61P25/28;C07K16/18;C12Q1/02;(IPC1-7):A61K39/395 |
主分类号 |
A61K31/195 |
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