PYRROLOPYRIMIDINONE DERIVATIVE

摘要

A compound represented by the following formula, which has inhibitory activi ty against GSK-3. (I) In the formula, A1 and A3 each is a single bond or an aliphatic hydrocarbon; A2 and A4 each is a single bond, CO, COO, etc.; G1 is a single bond, alicyclic hydrocarbon, aromatic hydrocarbon, etc.; G2 is hydrogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, etc.; A5 is a single bond or NR; R2 is hydrogen, halogeno, an aliphatic hydrocarbon, etc.; A6 is a single bond, NR, CO, etc.; and R3 is hydrogen, halogeno, nitro, a saturated aliphatic hydrocarbon, etc.; provided that R is hydrogen or a lower aliphatic hydrocarbon group.