| 发明名称 |
TARGETED MHC CLASS I ALPHA3 VACCINE DELIVERY SYSTEMS |
| 摘要 |
The present invention is directed to a novel targeted vaccine delivery system, comprising one or more isolated MHC class I alpha3 domains linked to an antibody which is specific for a cell surface marker and associated with beta2-microglobulin and antigenic peptides, or costimulatory molecules, or cytokines. The complexes of the invention are useful for treating and/or preventing cancer, infectious diseases, autoimmune diseases, and/or allergies. |
| 申请公布号 |
WO2004087058(A2) |
申请公布日期 |
2004.10.14 |
| 申请号 |
WO2004US09385 |
申请日期 |
2004.03.26 |
| 申请人 |
ZAUDERER, MAURICE;PARIS, MARK J.;SMITH, ERNEST S. |
发明人 |
ZAUDERER, MAURICE;PARIS, MARK J.;SMITH, ERNEST S. |
| 分类号 |
A61K;A61K38/00;A61K39/00;A61K39/145;A61K39/25;A61K39/38;A61K39/40;C07K14/045;C07K14/74;C07K16/28;C07K16/46;C12P21/08 |
主分类号 |
A61K |
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