发明名称 |
METHODS FOR BLOCKING ADIPOCYTE DIFFERENTIATION AND TRIGLYCERIDE ACCUMULATION WITH DUAL-SPECIFICITY TYROSINE- (Y) - PHOSPHORYLATION REGULATED KINASE 4 (DYRK4) INHIBITORS |
摘要 |
Methods for blocking adipocyte differentiation and triglyceride accumulation with inhibitors of DYRK4 are provided. DYRK4 inhibitors of the present invention include small molecules, antibodies, peptides (including dominant negative peptides) and antisense compounds, including ribozymes, inhibitory RNA molecules including siRNA molecules and antisense oligonucleotides. |
申请公布号 |
WO2004029070(A2) |
申请公布日期 |
2004.04.08 |
申请号 |
WO2003US29889 |
申请日期 |
2003.09.23 |
申请人 |
ISIS PHARMACEUTICAL, INC.;MARCUSSON, ERIC, G.;DEAN, NICHOLAS, M. |
发明人 |
MARCUSSON, ERIC, G.;DEAN, NICHOLAS, M. |
分类号 |
A61K48/00;C07K;C12N15/113 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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