发明名称 |
Inhibition of a target messenger RNA with a modified U1 small nuclear RNA |
摘要 |
Methods of reducing gene expression, protein production and messenger RNA output in a cell are disclosed. Also disclosed is a method for delivering a selected ribozyme to a target mRNA in a cell. The methods are useful for prophylactic and therapeutic purposes.
|
申请公布号 |
US6692910(B2) |
申请公布日期 |
2004.02.17 |
申请号 |
US19980123064 |
申请日期 |
1998.07.27 |
申请人 |
THE UNIVERSITY OF CONNECTICUT |
发明人 |
ROWE DAVID W.;STOVER MARY LOUISE;BECKLEY AKIN |
分类号 |
A61K38/00;C12N15/113;C12N15/63;(IPC1-7):C12Q1/68;C07H21/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|