The invention provides methods and compositions for reductively deoxygenating an amide group at a C-3' position of a taxane molecule followed by subsequent intra-molecular acyl migration of an acyl group to the C-3' position.
申请公布号
WO03087079(A1)
申请公布日期
2003.10.23
申请号
WO2003US10557
申请日期
2003.04.05
申请人
NATURAL PHARMACEUTICALS, INC.;JOHNSON, JAMES, H.;GALLAGHER, REX, T.;FRANKE, ROLAND, R.
发明人
JOHNSON, JAMES, H.;GALLAGHER, REX, T.;FRANKE, ROLAND, R.