| 摘要 |
<p>It is intended to provide a highly accurate, reproducible, economically advantageous and echo-friendly method of purifying an oxidatively injured guanine nucleoside; a method of measuring the same; and an analyzer for embodying these methods. Namely, a method of purifying an oxidatively injured guanine nucleoside formed by an injure to guanine in DNA or RNA which is characterized by having the first purification step of purifying the oxidatively injured guanine nucleoside in a sample by anion exchange chromatography. A method of purifying 8-OH-dG contained in a sample characterized in that 8-OH-rGuo is preliminarily added to the sample followed by the purification. A method of measuring oxidatively injured guanine nucleoside characterized by having the measurement step of measuring oxidatively injured guanine nucleoside having been purified by the above-described purification method.</p> |
