| 发明名称 |
BISPECIFIC MONOCLONAL ANTIBODIES TO IL-12 AND IL-18 |
| 摘要 |
A bispecific monoclonal antibody is described which comprises two moieties, one of which comprises an antigen-binding region which is specific for either the IL-12 beta 1 or the IL-12R beta 2 subunit of an IL-12 receptor, and the other of which comprises an antigen-binding region which is specific for either the IL-18R or the AcPL subunit of an IL-18 receptor. |
| 申请公布号 |
WO03008452(A2) |
申请公布日期 |
2003.01.30 |
| 申请号 |
WO2001US22862 |
申请日期 |
2001.07.20 |
| 申请人 |
SCHERING AKTIENGESELLSCHAFT;LEUNG, STEWART;PEREZ, H., DANIEL;MIYAMOTO, NEIL |
发明人 |
LEUNG, STEWART;PEREZ, H., DANIEL;MIYAMOTO, NEIL |
| 分类号 |
G01N33/53;A61K39/395;A61K45/00;A61P25/00;A61P29/00;A61P37/00;A61P37/06;A61P43/00;C07K16/24;C07K16/28;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12N15/09;C12N15/13;C12P21/02;C12P21/08;G01N33/577;G01N33/68 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
