摘要 |
The invention relates to a probe for the analysis of one or more proteins by laser desorption/ionisation mass spectrometry. The proteins include a tag, which in turn include a biotin group. The probe includes at least one surface including one or more of streptavidin, avidin or neutravidin molecules to bind the biotin group to the surface. The proteins can also carry a BCCP tag. The probe can form a protein array of two or more proteins at know locations on the surface of a chip. The invention also relates to methods of analysis by laser desorption/ionisation mass spectrometry using the probe. A scalable MALDI target volume sample volume loading kit and methods for its use are provided herein. |