INHIBITION OF PROTEASOMES WITH 26S- AND 20S-INDANONES

摘要

FIELD: organic chemistry, medicine. SUBSTANCE: invention proposes method of treatment of mammals with damages of cellular proliferation, disorders of immune system and infectious diseases that involves administration of therapeutically effective amount of compound of the formula (I) . Invention proposes also compositions based on thereof. Method does not cause unfavorable toxicological effects but shows effectiveness in disorders associated with accelerated cellular proliferation. EFFECT: enhanced method of treatment. 39 cl, 2 tbl, 3 dwg, 5 ex