It is intended to provide antiinflammatory agents for airway, foods and drinks, animal feeds, food additives, feed additives and a method of preventing or treating airway inflammation. The above object is achieved by providing antiinflammatory agents for airway, foods and drinks, animal feeds, food additives and feed additives each containing orotic acid or its derivatives or salts of the same as the active ingredient, and a method of preventing or treating airway inflammation characterized by administering orotic acid or its derivatives or salts of the same.