摘要 |
The present invention is concerned with a kit containing a plurality of hormone units for use in a contraceptive method which consists of two alternating consecutive phases, sometimes referred to as a sequential method or sequential regimen. More particularly the present invention relates to a kit containing a plurality of daily hormone units for use in a contraceptive method which consists of two alternating consecutive phases - an estrogenic and a progestogenic phase - of administering a sequence of said hormone units to a female of childbearing capability, the plurality of daily hormone units consisting of: (a) one or more daily hormone units, for use during the estrogenic phase, containing synthetic estrogen or a combination of synthetic estrogen and biogenic estrogen in a therapeutically effective amount to inhibit ovulation and (b) at least 10 daily hormone units, for use during the progestogenic phase, containing a combination of biogenic estrogen and progestogen in a therapeutically effective amount to inhibit ovulation and to transform the endometrium from a proliferative into a secretory state.
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申请人 |
PANTARHEI BIOSCIENCE B.V.;VAN BEEK, AGATHA, ANTONIA, MAGDALENA;COELINGH BENNINK, HERMAN, JAN, TIJMEN |
发明人 |
VAN BEEK, AGATHA, ANTONIA, MAGDALENA;COELINGH BENNINK, HERMAN, JAN, TIJMEN |