| 发明名称 |
1,4,5,6-TETRAHYDROPYRAZOLO-[3,4-C]-PYRIDIN-7-ONES AS FACTOR XA INHIBITORS |
| 摘要 |
The present application describes 1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin -7- ones of Formula (I) or pharmaceutically acceptable salt forms thereof, where in ring R is 3-amido or 4-methoxy, R1 is trifluoromethyl or amido, and R2 is aminomethyl, N-methylaminomethyl, and N,N-dimethylaminomethyl. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
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| 申请公布号 |
CA2441772(A1) |
申请公布日期 |
2002.10.31 |
| 申请号 |
CA20022441772 |
申请日期 |
2002.04.17 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PINTO, DONALD J.;GALEMMO, ROBERT A. |
| 分类号 |
A61P7/02;C07D471/04;(IPC1-7):C07D471/04;C07D221/00;C07D231/00;A61P9/00;A61K31/415;A61K31/416;A61K31/437 |
主分类号 |
A61P7/02 |
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