发明名称 |
METHODS FOR COMPARING GENE EXPRESSION LEVELS OR PATERNS IN NORMAL OR TUMOR CELLS |
摘要 |
<p>The invention concerns a method of determining the presence or absence of a biological condition in humans, in particular of colon cancer, and of determining the stage of a condition in human tissue by determining an expression pattern of a cell sample. Further, the invention relates to a method of determining the presence or absence of a biological condition in human tissue, and of determining the stage of a biological condition in human tissue, and also for reducing biological abnormalities of a cell suffering from the biological condition. A method for producing antibodies against an expression product of a cell from the tissue is also described. The invention also discloses a pharmaceutical composition for the treatment of a biological condition comprising at least one antibody, and a vaccine for the prophylaxis or treatment of a biological condition. Further the invention describes the use of a method for producing an assay for diagnosing a biological condition in human tissue, the use of a peptide or a gene or a probe for the preparation of a pharmaceutical composition for the treatment of a biological condition in human tissue, and an assay for determining the presence or absence of biological condition in human tissue and for determining an expression pattern of a cell.</p> |
申请公布号 |
EP1246937(A2) |
申请公布日期 |
2002.10.09 |
申请号 |
EP20000984938 |
申请日期 |
2000.12.29 |
申请人 |
AROS APPLIED BIOTECHNOLOGY APS |
发明人 |
OERNTOFT, TORBEN, F;THYKJAER, THOMAS;DEMTROEDER, KARIN;FREDERIKSEN, CASPER MOELLER |
分类号 |
C12Q1/68;G01N33/574;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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