发明名称 |
Analyse von Modifizierungen und Demodifizierungen von Proteinen mit Ubiquitinverwandten Proteinen mittels FRET (Fluorescence Resonance Energy Transfer) |
摘要 |
The invention relates to a method for analysing modifications of proteins with ubiquitin-related proteins and demodification of proteins which are concatenated with ubiquitin-related proteins. The invention also relates to a method for determining substances which influence said modifications or demodifications, in addition to a method for detecting a defect in said modifications or demodifications. Furthermore, the invention relates to a method for identifying target proteins for modification with ubiquitin-related proteins and a method for producing a pharmaceutical composition. The invention further relates to a kit, a fusion protein, a cell and an isopeptidase substrate and the use thereof in the analysis and/or diagnosis of modification or demodification of proteins with ubiquitin-related proteins.
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申请公布号 |
DE10108263(A1) |
申请公布日期 |
2002.09.05 |
申请号 |
DE20011008263 |
申请日期 |
2001.02.21 |
申请人 |
MAX PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
MELCHIOR, FRAUKE;GAERTNER, ULRIKE;BUESGEN, TANJA;GAST, ANDREAS;PICHLER, ADREA;SCHERGAUT, MARION;SWAMINATHAN, SOWMYA |
分类号 |
G01N33/542;G01N33/68;(IPC1-7):C07K19/00 |
主分类号 |
G01N33/542 |
代理机构 |
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