发明名称 THROMBIN INHIBITORS
摘要 <p>Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure Formula (I): wherein u is CH or N; Q is 1)-N(R&lt;Sup&gt;25&lt;/Sup&gt;)CH(R&lt;Sup&gt;30&lt;/Sup&gt;)- wherein the nitrogen atom is attached to R&lt;Sup&gt;1&lt;/Sup&gt;, and R&lt;Sup&gt;25&lt;/Sup&gt; and R&lt;Sup&gt;30&lt;/Sup&gt; are independently selected from the group consisting of hydrogen, C&lt;Sub&gt;3-6&lt;/Sub&gt;cycloalkyl, and C&lt;Sub&gt;1-6&lt;/Sub&gt;alkyl, or 2) wherein the nitrogen atom is attached to R&lt;Sup&gt;1&lt;/Sup&gt;, and m is 0, 1, or 2.</p>
申请公布号 WO2002064559(A3) 申请公布日期 2002.08.22
申请号 US2002/004658 申请日期 2002.02.05
申请人 发明人
分类号 C07D403/12;A61K31/41 主分类号 C07D403/12
代理机构 代理人
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