DRUGS FOR THE DIAGNOSIS OF TISSUE-REPRODUCTIVE ACTIVITY OR THE TREATMENT OF PROLIFERATIVE DISEASES

摘要

Drugs containing as the active ingredient radioactively labeled compounds of the following general formula or pharmaceutically acceptable salts thereof: [wherein R1 is hydrogen or linear or branched C1-8 alkyl; R2 is hydrogen, hydroxyl, or halogeno; R3 is hydrogen or fluoro; R4 is oxygen, sulfur, or methylene; and R5 is radioactive halogeno]. The drugs are stable in the living body, and stay in the cell or are integrated into DNA, thus being useful in the diagnosis of tissue-reproductive activity or the treatment of proliferative diseases.