| 发明名称 |
In vivo stimulation of angiogenic activity |
| 摘要 |
Angiogenesis is stimulated by introducing two replication-deficient adenovirus vectors to the endothelial cells or proximate to the endothelial cells of an organism. The first vector encodes VEGF-B167 or a fragment or conservative substitution thereof, the second vector encodes VEGF-A or VEGF-C, or fragments or conservative substitutions thereof. |
| 申请公布号 |
AU2447102(A) |
申请公布日期 |
2002.05.15 |
| 申请号 |
AU20020024471 |
申请日期 |
2001.11.01 |
| 申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH;AVENTIS PHARMA S.A.;LICENTIA LTD. |
发明人 |
BERNDT ENHOLM;DIDIER BRANELLEC;SEPPO YLAE-HERTTUALA;RALF PETTERSSON;ERIKA BERGSTEN;ULF ERIKSSON;KARL ALITALO;AUDE LE ROUX |
| 分类号 |
C12N15/09;A61K31/70;A61K35/76;A61K38/19;A61K48/00;A61P43/00;C07K14/515;C07K14/52;C12N15/861;(IPC1-7):A61K31/70;A01N43/04;C12N15/63;C12N15/86 |
主分类号 |
C12N15/09 |
| 代理机构 |
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