摘要 |
PROBLEM TO BE SOLVED: To provide a method of producing 3,4-methylenedioxy-mandelic acid by allowing 1,2-methylenedioxybenzene to react with a liquid mixture of strong acid and glyoxylic acid in an organic solvent in high yield in an industrial scale. SOLUTION: 1,2-Methylenedioxybenezene is allowed to react with a mixture of strong acid and 50-80 wt.% of glyoxylic acid aqueous solution in an organic solvent to give the objective 3,4-methylenedioxymandelic acid.
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